Reduced CXCR1 (CXC chemokine receptor 1) and CXCR3 (CXC chemokine receptor 3) expression was associated with a smaller tumor size and lower tumor stage (TNM) stage, while decreased CXCR2 (CXC chemokine receptor 2) and CXCR4 (CXC chemokine receptor 4) expression correlated with a larger tumor and higher TNM stage. The gene discussed is CXCR2; the disease is neoplasm.