FLT3 and rheumatoid arthritis: Due to the properties of-anti-inflammation and anti-Flt3-mediated pathway as well as the traditional rheumatism application of Croton tiglium extract, we postulated that crotonoside could be a potential bioactive agent for RA treatment and might have a strong association in the regulation of immune cells, particularly DCs, to exert their anti-arthritic effects.