Among anti-IL-17 drugs, the ones that simultaneously block more subunits of anti-IL-17, such as Bimekizumab, may be more effective in the treatment of HS, as the various subunits seems equally involved in the development of inflammation, and bimekizumab seems to have a major effectiveness in suppressing inflammation and cytokine production from preclinical studies [103]. This evidence concerns the gene IL17A and histiocytic sarcoma.