FGF2 and diabetes mellitus: In addition, it has been reported that BLT2 agonist directly promotes keratinocyte migration and indirectly enhances fibroblast proliferation by increasing the keratinocyte production of transforming growth factor-β1 (TGF-β1) and basic fibroblast growth factor (bFGF) and thus accelerated wound closure in a rat model of streptozotocin-induced diabetes [59].