CSF3 and cancer: Moreover, the same document of The National Health Service England in collaboration with The European Society of Medical Oncology suggested that oncologists should give higher priority to treat cancer patients clinically unstable and consider to change intravenous treatments to subcutaneous or oral administrations (possibly with longer intervals between cancer treatments (immune checkpoint inhibitors, or ICIs) with the use of granulocyte colony-stimulating factor (GCSF) as primary prophylaxis in these patients [20].