Interleukin-7 (IL-7) is a key regulator of T-cell growth [114]; IL-7 recruits monocytes and macrophages to the endothelium and plays a crucial role in the pathogenesis of atherosclerosis through the Phosphoinositide 3-kinases (PI3K)-AKT and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB) pathways [114]; in another study, IL-7 promoted clinical instability in patients with coronary artery disease [115]. This evidence concerns the gene IL7 and coronary artery disorder.