RRM2 and spindle cell hemangioma: The hsa-miR-let-7c-5p and hsa-miR-215-5p were identified regulating most of the differentially expressed genes found between SCC and SCH (Figure 4) and were closely related to the carcinogenic pathway, regulating the expression of RRM2, PMAIP1, CDKN2A, CCNE1, and CCND1 (Figure 9).