The hsa-miR-let-7c-5p and hsa-miR-215-5p were identified regulating most of the differentially expressed genes found between SCC and SCH (Figure 4) and were closely related to the carcinogenic pathway, regulating the expression of RRM2, PMAIP1, CDKN2A, CCNE1, and CCND1 (Figure 9). The gene discussed is PMAIP1; the disease is spindle cell hemangioma.