However, as reported by the 13th International Congress on Antiphospholipid Antibodies, the test for IgA-anti-β2-GPI should be considered useful in patients negative for IgG and IgM isotypes with APS symptoms, thus could be considered as a non-criteria test to detect aPL in SN-APS patients [145] (Table 1). The gene discussed is CD79A; the disease is autoimmune polyendocrinopathy.