APOH and autoimmune polyendocrinopathy: Moreover, anti-β2GPI (ILA-1, ILA-3 and H-3 MoAb), that are able to interact specifically with three different hexapeptides corresponding to distinct epitopes located in domains I-II, III and IV of the molecule [64,65], are able to activate endothelial cells in vitro and induce experimental APS by passive transfer [66].