CD8A and neoplasm: The combination of exosomes and the invariant NKT immune cell ligand α-galactosylceramide (αGC) induced potent NK and γδ T cell innate immune responses in vitro and in vivo, and they increased survival by increasing antigen-specific CD8+ T cell tumor infiltration while decreasing tumor growth in an ovalbumin (OVA)-expressing tumor-bearing mouse model [27].