Some of the prime molecules that foster pro-tumor immunity in the ovarian TME are vascular endothelial growth factor (VEGF), indoleamine-2,3-dioxygenase (IDO), transforming growth factor beta (TGF-β) and interleukin 10 (IL-10), which are secreted by cells such as immunosuppressive TAMS, CD4+ CD25high FoxP3+ Tregs, and pDCs [103]. The gene discussed is CD4; the disease is neoplasm.