We replicated the association signal at IKZF3 in a EA (European-American) SLE ImmunoChip cohort (ncases = 6748, ncontrols = 11,516), with a total of 93 tag-SNPs in LD with rs2941509 (ORrs2941509 = 1.27, CI 1.14–1.41) showing highly significant association (Table A4). Here, IKZF3 is linked to systemic lupus erythematosus.