In addition, we selected age, sex, and smoking history as covariates, which have been reported to be associated with ILA in previous studies.12,13,14 This model showed ILA as an independent risk factor for ICI-ILD (OR, 6.42; 95% CI, 1.96-21.03; P = .01) (Table 4). The gene discussed is TNFRSF9; the disease is interstitial lung disease.