IFNA1 and cancer: Additionally, by binding to IFN‐α and IFN‐β receptors (IFNAR I) on cancer cells, type I IFNs trigger autocrine and paracrine signaling pathways culminating in the expression and release of IFN‐stimulated genes (ISGs) including the T‐cell chemoattractant chemokine C‐X‐C motif ligand 10 (CXCL10).