A study by Hicks et al of 32 patients with known prostate cancer ahead of radical prostatectomy found that 68Ga-PSMA PET/MRI detected prostate cancer in 97% of patients with the disease vs 79% by multiparametric MRI alone, using whole organ pathology as the gold-standard.55 Particularly with the increasing prevalence of PET/MR scanners, this modality may provide not only increased sensitivity for prostate cancer, but also a "one-stop shop" in which both localized disease and regional or distant metastases are diagnosed in a single study. The gene discussed is FOLH1; the disease is Familial prostate cancer.