Importantly, the lungs of BPD mice exhibit predominantly type 2 immune responses, including increased Th2 chemokine levels [17], intense eosinophilic infiltration, Th2 hyperpolarization [18], the cytokines IL-4 and IL-13 [19], and M2 macrophages enrichment [20]. The gene discussed is IL13; the disease is bronchopulmonary dysplasia.