In BPD mice treated with IL-33, the structure of alveoli was disordered, the fusion of alveoli was larger, the number was reduced, the structure was simplified, the alveoli wall was thickened, and the inflammatory cells were increased, while the opposite was true in BPD mice treated with anti-ST2 antibody (Figure 3(b)). The gene discussed is IL33; the disease is bronchopulmonary dysplasia.