Prominently, positive correlations were detected between serum GDF15 levels and TBIL (r = 0.733, p = 0.0002), GDF15 and DBIL (r = 0.786, p < 0.0001), and GDF15 and TBA (r = 0.585, p = 0.007) in cirrhotic PBC patients (see Figures 2(a)–2(c)). The gene discussed is GDF15; the disease is primary biliary cholangitis.