Moreover, serum levels of GDF15 were significantly higher in PBC patients with decompensated cirrhosis than in PBC patients with compensated cirrhosis (6679.31 ± 828.27 vs. 2784.04 ± 477.06 pg/mL; p < 0.001) (see Figure 1(c)). This evidence concerns the gene GDF15 and primary biliary cholangitis.