In the present study, we found that there were negative relationships between ALB and GDF15 (r = −0.775, p < 0.0001) (see Figure 2(d)) and GDF15 and weight changes (r = −0.541, p = 0.0138) (see Figure 2(e)) in cirrhotic PBC patients but a positive relationship between CRP and GDF15 (r = 0.718, p = 0.0005) (see Figure 2(f)). Here, ALB is linked to primary biliary cholangitis.