LDLR and hyperlipidemia: The results of our lipid deposition assays showed that CD68 and CD36 expression and PAS staining were significantly increased in the LDL-R−/− HFD group compared with those in the LDL-R−/− ND group; however, this damage was significantly inhibited in the HFD+TQ group, indicating that TQ inhibits the cardiac damage caused by hyperlipidemia by inhibiting lipid deposition and the conversion of macrophages to foam cells.