The C-index of the nomogram for RFS was 0.649, which was statistically higher than the PLR (0.549), AFP (0.564), tumor encapsulation (0.561), tumor diameter (0.582), HBV-DNA (0.542), tumor number (0.538), ishak inflammation score (0.567) and MVI (0.559) (all P < 0.001). This evidence concerns the gene AFP and neoplasm.