As for the OS, the C-index of the nomogram was 0.716, which was statistically higher than the PLR (0.559), aspartate aminotransferase (0.591), AFP (0.584), tumor encapsulation (0.591), HBV-DNA (0.569) and tumor diameter (0.635) (all P < 0.001). This evidence concerns the gene AFP and neoplasm.