When tumor infiltration by CD8+ T-cells between the high and low PLR groups were compared, there was no significant difference in intratumoral CD8+ T-cell counts between the two groups (18.9 ± 5.4 vs. 19.3 ± 3.3 P = 0.845; Figures 3B,D,G). This evidence concerns the gene CD8A and neoplasm.