While mRNA expression of the pro-inflammatory cytokine TNF-α and IL-1β were greatly induced upon infection with either L.m. or C. acnes strains NCTC737 or Asn12 as well as upon stimulation with LPS, the induction of a type-I IFN response was only upregulated upon LPS treatment which could neither be seen with L.m. nor with any of the two C. acnes strains used (Supplementary Figure S2A). Here, IL1B is linked to infection.