et al. (15) established a subcutaneous skin/skin structure abscess model that utilized a Methicillin-resistant S. aureus (MRSA) strain, and found that IL-17A and IL-22 helped to control the severity of abscesses; nevertheless, inhibition of IL-17A or IL-22 alone resulted in larger lesion areas (skin necrotic areas). The gene discussed is IL22; the disease is abscess.