Separate inhibition or knockdown of ASIC1 and ASIC3 decreased the acidity-promoted invasion and migration capacity of PDAC cell lines, but did not decrease the proliferation rate, suggesting that ASIC1 and ASIC3 are involved in the metastatic process of PDAC, but not tumor cell growth (Zhu et al., 2017). Here, ASIC3 is linked to neoplasm.