Inhibit cell proliferation, migration, invasion and induce apoptosis; impair the traits of cancer stem-like cells; reduce the expression of YAP, p-YAP, CTGF, CYR61, bcl-2, bcl-XL protein levels and increase c-PARP, c-caspase3, Cyto c, BAX. The gene discussed is BCL2; the disease is cancer.