Other significant prognostic factors for all-cause mortality were age (HR: 1.031), ECOG grade ≥ 1 (HR: 1.495), preoperative carcinoembryonic antigen (CEA) level (HR: 1.830, on base-10 logarithmic scale), cancer stage (II vs. I, HR: 1.985; III vs. I, HR: 3.086), microscopic necrosis (HR: 1.473), lymphovascular invasion (HR: 2.006), and anesthesia time (HR: 1.702, on base-2 logarithmic scale). This evidence concerns the gene CEACAM5 and cancer.