Interleukin (IL)-17 is a pro-inflammatory cytokine produced mainly by Th17 cells, which promotes immunity to extracellular microbes, especially fungi47. In rohu following experimental infection with A. invadans, a number of transcription factors involved in mediation of IL-17 downstream signaling including CEBPB, JUN as well as NFKBIA were upregulated. The gene discussed is IL17A; the disease is infection.