Consistent with previous reports of fibrates, these findings indicated that the GW7647 treatment groups experienced an amelioration in steatosis induced by HF-CDAA via the induction of both hepatic ACOX1, is the first and rate-limiting enzyme in fatty acid β-oxidation in peroxisomal, and CPT1, 2, controls mitochondrial beta-oxidation. Here, ACOX1 is linked to steatosis.