HF-CDAA-induced phosphorylation of NF-κB p65 at Ser536, that of Erk1/2 at Thr202/Tyr204, and that of JNK at Thr183/Tyr185 were abrogated in the livers of mice in the co-treatment group (Fig. 3D). Here, MAPK8 is linked to hydrops fetalis.