SEMA4C and neoplasm: As shown in Table 1, SEMA4C mRNA expression was significantly associated with the histological tumor type (P = 0.019), pathologic stage (P = 0.008), lymph node metastasis (P = 0.011), distant metastasis (P = 0.013), microsatellite instability (MSI) status (P = 0.038) and CMS subtypes (P = 2.091E-9).