AKT1 and cancer: Moreover, the significantly enriched KEGG pathways contained Ras signaling pathway, focal adhesion, phosphatidylinositol 3-kinase (PI3K)-Akt signaling pathway, proteoglycans in cancer, bladder cancer, pathways in cancer, vascular endothelial growth factor (VEGF) signaling pathway, adherens junctions, and erb-b2 receptor tyrosine kinase (ErbB) signaling pathway (Figure 4C).