In the prior clinical trial of VRP-CEA(6D) enrolling patients with metastatic malignancies (predominantly colon cancer), we observed vaccine-induced adaptive immunity and reported longer survival for those with CEA-specific T cell responses (details and demographics previously published).12 We now update their survival, with median follow-up of 10.9 years; 95% CI (9.6 to 11.4) with 10-year survival of 0.14; 95 % CI (0.04 to 0.29). The gene discussed is CEACAM5; the disease is colonic neoplasm.