UbMPO induces IFNγ and IL-17A production as well a differential proliferation and activation profile: By means of intracellular cytokine staining, increased production of IFNγ (Fig. 1a) and IL-17A (Fig. 1b) was found in SLE CD4+ T lymphocytes co-cultured with dendritic cells activated with rhMPO and UbMPO compared to the group in which the co-culture included DC activated only with LPS (p < 0.05). This evidence concerns the gene IFNG and systemic lupus erythematosus.