IFNG and systemic lupus erythematosus: Higher IFNγ production was found in total PBMCs that were stimulated with NETs from lupus patients that previously had shown to contain ISG15 (Fig. 4b) compared to cells stimulated with NETs from healthy controls (Fig. 4c) (%IFNγ 6.5[6.31–10.1] vs 3.5[1.7–5.1]) p < 0.05).