While there is no current clinical trial for testing CD70-specific CAR-T cells in GBM, phase I/II clinical trials are underway to study the safety and efficacy of CD70-specific CAR-T cell therapy in B cell cancers (NCT03125577, NCT04429438) as well as pancreatic, renal, breast and ovarian cancers (NCT02830724). This evidence concerns the gene CD70 and ovarian carcinoma.