To further elucidate the mechanism how HNF1B influences the cell cycle, we re‐explored and analysed the RNA‐seq data, and focused on Cyclin D1, which a key regulator of cell cycle (G1‐ phase) for both normal and tumour cells, is negatively regulated by HNF1B in prostate cancer cells. Here, HNF1B is linked to prostate carcinoma.