Recent years, genome‐wide association studies (GWAS) and fine‐mapping analysis have identified several distinct variants within HNF1B gene associated with increased risk of prostate cancer, such as rs11649743 and rs4430796,3, 4, 5, 6, 7, 8, 9 which suggest that HNF1B has potential roles in prostate cancer progression. The gene discussed is HNF1B; the disease is prostate carcinoma.