In recent years, the results of genome‐wide association studies (GWAS) and fine‐mapping analysis have found that several different variants in the HNF1B gene are associated with the genetic risk of prostate cancer,3, 4, 5, 6, 7, 8, 9 which suggest that HNF1B has potential roles in prostate cancer progression. This evidence concerns the gene HNF1B and Familial prostate cancer.