Upon analysis of the DEGs, we identified 11 major cell types: breast cancer cells (i.e., expressing Epcam; BCs), CAFs (i.e., expressing Col1A1, Col3A1, THY1, and FAP), natural killer T (NKT) cells, T cells, B cells, vascular endothelial cells (VECs), adipocyte stem cells (ASCs), adipocytes, macrophages (Mφ), dendritic cells and neutrophils (Figure 2A). The gene discussed is COL3A1; the disease is breast cancer.