In the previous work, we and others have identified a subpopulation of tumor cells in OPC‐derived glioma models by both bulk RNA sequencing and in situ immunofluorescence staining.[4, 7, 8, 25] We could here assign this subpopulation to the cluster 7 on the t‐SNE map of the scRNA‐seq dataset based on their coexpression of both tdTomato and OPC makers including PDGFRα and CSPG4 (NG2) (Figure 1D–G; Figure S1, Supporting Information). This evidence concerns the gene CSPG4 and central nervous system cancer.