These observations are also consistent with cytokine array analysis in lung tissue from the CLP‐operated mouse model, which revealed that DNase‐I pMNS treatment lead to a reduction in the level of sepsis‐related pro‐inflammatory cytokines, such as IL‐6, IL‐8, IL‐1β, and CCL2 (Figure 4). This evidence concerns the gene CXCL8 and Sepsis.