Significant treatment effects were observed, parathyroid hormone levels were significantly decreased when compared to the baseline. Anti-inflammatory cytokine IL-10 was significantly higher in the intervention group at 9 months and pro-inflammatory cytokine TNF-a was increased in controls but remain constant in the therapy group. Vitamin D reduced the inflammatory state in CHF patients and might be a new anti-inflammatory agent in the future. But during follow-up at 15 months, the survival rate did not differ significantly. The gene discussed is TNF; the disease is congestive heart failure.