Growth differentiation factor-10 (GDF10), also known asbone morphogenetic protein 3B (BMP-3B), inhibits vimentin expression and themigration and invasion of squamous cell carcinoma of the head and neck andincreases E-cadherin expression and the sensitivity of tumor cells to cytotoxictherapy through apoptosis induction. The gene discussed is GDF10; the disease is squamous cell carcinoma.