In a recent study that used a mouse reporter line as an in vivomodel of pancreatic cancer, Aiello et al. [107] confirmed the possibility that two EMT types areutilized during tumor invasion: complete EMT characterized by reducedE-cadherin transcription and increased vimentin transcription, and partial EMTcharacterized by the preserved expression of E-cadherin mRNAs and increasedvimentin transcription (partial EMT is also characterized by a lower expressionof the transcriptional factors Etv1, Prrx1, Zeb1, Twist1, Snai1, Snai2, andZeb2, compared with complete EMT). The gene discussed is ZEB1; the disease is familial pancreatic carcinoma.