The combination of curcumin and (-)-epigallocatechin-3-gallate (EGCG) has anti-angiogenic activities in colorectal carcinoma by blocking the Janus kinase/Signal transducer and activator of transcription 3/Interleukin-8 (JAK/STAT3/IL-8) pathway 9. Here, CXCL8 is linked to colorectal carcinoma.