Indeed, the DRP markers such as Prom1, EpCAM, Krt19, and Sox9 detected in AH, were also induced in non-tumor liver tissue (NTL) of mice subjected to DEN injection and tumor promotion with WAD as compared to normal liver or tumor tissues, suggesting a more selective increase of DRPs in NTL (Fig. 2a). This evidence concerns the gene PROM1 and neoplasm.