The progress from pyuria Group 0 to pyuria Group 2 was associated with a gradual increase in the percentage of comorbidities, including ischemic heart disease, congestive heart failure, diabetes mellitus (DM), cancer, hypertension, and CV disease and an increase in age, C-reactive protein (CRP), phosphorus, and UPCR (Table 2). This evidence concerns the gene CRP and coronary artery disorder.