There was no difference in HYAL-1 concentrations between the non-obese (N = 25; 0.61/0.36–0.86/ng/mL) and obese (N = 43; 0.54/0.31–0.89/ng/mL) patients with OSA (p = 0.68). This evidence concerns the gene HYAL1 and obstructive sleep apnea syndrome.