HYAL1 and obstructive sleep apnea syndrome: There was a significant correlation between HYAL-1 and BMI in the total cohort of subjects (r = 0.25; p = 0.01); however, this correlation became insignificant when controls (r = 0.25; p = 0.12) or patients with OSA (r = 0.06; p = 0.65) were investigated separately.