Frequently affected genes by CNVs in Chinese breast cancer patients were ERBB2 (25%), MIEN1 (25%), GRB7 (24%), TRPS1 (6%), MYC (6%), ERLIN2 (6%), PLPP5 (6%), NSD3 (6%), FGFR1 (6%), and CCND1 (5%). The gene discussed is GRB7; the disease is breast cancer.