CD86 and neoplasm: Gels incorporating Dox-iRGD with or without CpG roughly increased the number of activated (CD86+MHCII+) tumor-infiltrating CD11c+ DCs by 50% (Fig. 5d and Supplementary Fig. 13b–d) as compared to treatment with gels containing CpG alone or untreated tumors, although the total number of DCs remained unchanged (Supplementary Fig. 13a).