IGF2 and colorectal carcinoma: The IGF2 imprint was detected which separated CRC cells into IGF2 LOI and IGF2 MOI groups which showed Caco2 and HT-29 cells in IGF2 LOI group had a higher methylation in DMRs and IGF2 expression than Hct-8 and Hct-116 cells in IGF2 MOI group (p<0.05, Supplementary Figure 1).