We found 2.64-fold, 2.86-fold, and 0.65-fold increases in c-Fos, JunB, and c-Jun AP-1 family proteins, respectively, in primary WT Mφ infected with T. cruzi (versus no infection; P < 0.001) (Fig. 7D, G, and I). The gene discussed is JUND; the disease is infection.