SWIR imaging at 24-h and 36-h time points indicated differential localization of nanoprobes based on their distinct SWIR emissions, with increased accumulation of CAV1 targeted nanoprobes in the 4175TR tumor (Supplementary Fig. 7b), and increased accumulation of CXCR4 targeted nanoprobes in the MCF7 tumor (Supplementary Fig. 7d). The gene discussed is CAV1; the disease is neoplasm.