Only in 4T1 tumors from the 1000 IU+cal group was a significant decrease in VDR nuclear staining observed as compared to the 1000 IU group, whereas in E0771 tumor-bearing mice from the 100 IU+cal group increased VDR staining was found as compared to 100 IU (Suppl. The gene discussed is VDR; the disease is neoplasm.