These bioinformatics analyses demonstrated the inhibitory action of hsa-miR-133a-3p and hsa-miR-375-3p towards a total of 147 genes of which some are involved in several molecular and biological processes underlying tumor development, including TP53, SHANK2, CASP9, etc., whose dysregulation is notoriously observed in oral cancer [45,46,47]. This evidence concerns the gene TP53 and lip and oral cavity carcinoma.