Many molecules like myocyte injury markers troponins I and T, the myocyte stress markers brain natriuretic peptide (BNP) and ST2/IL-33, the inflammation markers C-reactive protein (CRP) and TNF, IL-1β, and IL-18 cytokines [40] have been examined as potential molecular markers for different cardiovascular disease, each of them diagnosing or predicting different cardiac disturbances like myocardial infarction, heart failure, or myocarditis. This evidence concerns the gene NPPB and cardiovascular disorder.