IL18 and heart failure: Many molecules like myocyte injury markers troponins I and T, the myocyte stress markers brain natriuretic peptide (BNP) and ST2/IL-33, the inflammation markers C-reactive protein (CRP) and TNF, IL-1β, and IL-18 cytokines [40] have been examined as potential molecular markers for different cardiovascular disease, each of them diagnosing or predicting different cardiac disturbances like myocardial infarction, heart failure, or myocarditis.