In a study on coronary heart disease, ANRIL (DQ485454) was demonstrated to regulate endothelial cell (EC) functions, including monocyte adhesion to ECs, transendothelial migration of monocytes and EC migration by regulating LYVE-1, as well as tube formation and migration transcription factors CLAP-GLY linker containing protein 1 (CLIP1) and ezrin (EZR) [91]. This evidence concerns the gene EZR and coronary artery disorder.