NRGN and Alzheimer disease: Ng was significantly elevated in patients with AD (n = 1894) in comparison to controls (n = 2051), and the differences were largest in that group (RoM: 1.62, 95% Confidence Intervals (CI) (1.50 to 1.75), z = 12.45, p < 0.001) (Figure 1A) (Supplementary Figure S1, Supplementary Table S3 (1.A)).