UBE3C and chronic kidney disease: The first block was composed of rs3802129/rs3815217, and the second block was composed of rs8101/rs7807 on the 3′-UTR of UBE3C. The rs3802129/rs3815217 (block 1) pairwise allele analysis revealed that patients with the A/G haplotype had a significantly higher risk of CKD phenotype compared with G/A haplotype (p value = 0.005; OR = 1.76; 95% CI = 1.19–2.61).