TGFB1 and Hepatic fibrosis: Expression levels of the let-7 family (let-7a-5p, let-7c-5p, and let-7d-5p) were inversely correlated with the degree of hepatic fibrosis due to HCV infection, and low expression of the let-7 family influenced hepatic fibrosis through activation of the TGF-β pathway in HSCs [80].